Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl (1S,5R)-9-hydroxy-9-[2-(3-methylphenyl)ethynyl]-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate
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Canonical SMILES
COC(=O)N1C[C@@H]2COC[C@H](C1)[C@@]2(O)C#Cc1cccc(C)c1
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Compound Formula C18H21NO4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3350 nM
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