Brief Information of the Compound and Protein
Compound Name
 Compound Info 
azetidin-1-yl-[(1R,5S)-3-hydroxy-3-[2-(3-methylphenyl)ethynyl]-8-azabicyclo[3.2.1]octan-8-yl]methanone
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Canonical SMILES
Cc1cccc(c1)C#C[C@@]1(O)C[C@@H]2CC[C@H](C1)N2C(=O)N1CCC1
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Compound Formula C20H24N2O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 210 nM
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