Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl (4aR,7aS)-3,3-difluoro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-2,4a,5,6,7,7a-hexahydrocyclopenta[b]pyridine-1-carboxylate
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 PubChem ID
CID: 76320761
Canonical SMILES
COC(=O)N1CC(F)(F)C(O)(C#Cc2cccc(C)c2)[C@@H]2CCC[C@H]12
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Compound Formula C19H21F2NO3
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 180 nM
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