Brief Information of the Compound and Protein
Compound Name
methyl (1R,5S)-3-hydroxy-3-[2-(3-methoxyphenyl)ethynyl]-8-azabicyclo[3.2.1]octane-8-carboxylate
    Show/Hide
Canonical SMILES
COC(=O)N1[C@H]2CC[C@@H]1C[C@](O)(C2)C#Cc1cccc(OC)c1
    Show/Hide
Compound Formula C18H21NO4
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 76.3 nM
   TI
   LI
   LO
   TS