Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl (3aS,6aR)-5-hydroxy-5-[2-(3-methylphenyl)ethynyl]-1,3,3a,4,6,6a-hexahydrocyclopenta[c]pyrrole-2-carboxylate
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 PubChem ID
CID: 76331633
Canonical SMILES
COC(=O)N1C[C@H]2CC(O)(C[C@H]2C1)C#Cc1cccc(C)c1
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Compound Formula C18H21NO3
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 8600 nM
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