Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(4-fluorophenyl)methyl]-3-oxo-1,1-diphenyl-5,6,8,8a-tetrahydro-[1,3]oxazolo[3,4-a]pyrazine-7-carboxamide
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 PubChem ID
CID: 11374217
SID: 16467496
Canonical SMILES
Fc1ccc(CNC(=O)N2CCN3C(C2)C(OC3=O)(c2ccccc2)c2ccccc2)cc1
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Compound Formula C26H24FN3O3
Compound Structure
Protein Name
 Protein Info 
Neuropeptide S receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
Q6W5P4
Gene Name
NPSR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
IC50 = 5.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 14 nM
   TI
   LI
   LO
   TS
3
IC50 = 25 nM
   TI
   LI
   LO
   TS
4
IC50 = 420 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 48 nM
2 Ki = 47.86 nM