Brief Information of the Compound and Protein
Compound Name
(+/-)-8-Fluoro-4-hydroxy-N-[4-(trifluoromethoxy)phenyl]-3,4-dihydro-1'H-spiro[chromene-2,4'-piperidine]-1'-carboxamide
    Show/Hide
PubChem ID
CID: 46917877
SID: 99383205
Canonical SMILES
O=C(Nc1ccc(OC(F)(F)F)cc1)N1CCC2(CC1)CC(O)c1cccc(F)c1O2
    Show/Hide
Compound Formula C21H20F4N2O4
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily M member 8
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q7Z2W7
Gene Name
TRPM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 22.5 nM
   TI
   LI
   LO
   TS