Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R)-3-[1-(3H-benzimidazol-5-ylmethyl)piperidin-4-yl]-1-cyclohexyl-4-phenylimidazolidin-2-one
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 PubChem ID
CID: 72712374
Canonical SMILES
O=C1N(C[C@H](N1C1CCN(Cc2ccc3nc[nH]c3c2)CC1)c1ccccc1)C1CCCCC1
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Compound Formula C28H35N5O
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 199.7 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 50.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 91 nM
   TI
   LI
   LO
   TS