Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R)-1-cyclohexyl-3-[1-[(4-phenoxyphenyl)methyl]piperidin-4-yl]-4-phenylimidazolidin-2-one
    Show/Hide
 PubChem ID
CID: 73355478
Canonical SMILES
O=C1N(C[C@H](N1C1CCN(Cc2ccc(Oc3ccccc3)cc2)CC1)c1ccccc1)C1CCCCC1
    Show/Hide
Compound Formula C33H39N3O2
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 135.9 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 13.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 22.5 nM
   TI
   LI
   LO
   TS