Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide
    Show/Hide
 PubChem ID
CID: 11245456
SID: 16330111
Canonical SMILES
O=C(Nc1cc(nn1-c1ccccc1)-c1ccccc1)c1cccc(c1)C#N
    Show/Hide
Compound Formula C23H16N4O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
2
EC50 = 27 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 250 nM