Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R,S)-2-phosphonomethylpentanedioic acid
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 PubChem ID
CID: 10130754
SID: 15121544
Canonical SMILES
OC(=O)CCC(CP(O)(O)=O)C(O)=O
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Compound Formula C6H11O7P
Compound Structure
Protein Name
 Protein Info 
Glutamate carboxypeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MH clan
>
Metallo protease M28 family
>
Metallo protease M28B subfamily
Uniprot ID
Q04609
Gene Name
FOLH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP
 Cell Line Info 
Homo sapiens (Human)  5
1
IC50 = 1.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 52 nM
   TI
   LI
   LO
   TS
3
Kd = 0.4 nM
   TI
   LI
   LO
   TS
4
Ki = 0.4 nM
   TI
   LI
   LO
   TS
5
Ki = 31.2 nM
   TI
   LI
   LO
   TS
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  1
1
Kd = 0.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 0.62 nM
2 IC50 = 0.3 nM
3 IC50 = 80 nM
4 Ki = 0.2 nM
5 Ki = 0.28 nM
6 Ki = 0.3 nM