Brief Information of the Compound and Protein
Compound Name
6-[[6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline
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PubChem ID
CID: 58955249
Canonical SMILES
Cn1cc(cn1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1
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Compound Formula C19H15N7
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 44 nM
   TI
   LI
   LO
   TS
CL000450 NCI-H441 Homo sapiens (Human)  1
1
IC50 = 69 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 210 nM
2 Ki = 74 nM