Brief Information of the Compound and Protein
Compound Name
2-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
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PubChem ID
CID: 2295463
SID: 16792031
Canonical SMILES
OC(=O)COc1ccc(\C=C2/SC(=O)NC2=O)cc1
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Compound Formula C12H9NO5S
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 349 nM
   TI
   LI
   LO
   TS
2
Ki = 50.8 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 1400 nM
   TI
   LI
   LO
   TS