Brief Information of the Compound and Protein
Compound Name
6-bromo-8-[(2-chloro-4-methoxybenzoyl)amino]-4-oxochromene-2-carboxylic acid
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PubChem ID
CID: 71733848
Canonical SMILES
COc1ccc(C(=O)Nc2cc(Br)cc3c2oc(cc3=O)C(O)=O)c(Cl)c1
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Compound Formula C18H11BrClNO6
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
>
Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
EC50 = 11.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 14.7 nM
   TI
   LI
   LO
   TS
3
Ki = 1.12 nM
   TI
   LI
   LO
   TS