Brief Information of the Compound and Protein
Compound Name
8-[(3,4-dichlorobenzoyl)amino]-6-fluoro-4-oxochromene-2-carboxylic acid
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PubChem ID
CID: 71733650
Canonical SMILES
OC(=O)c1cc(=O)c2cc(F)cc(NC(=O)c3ccc(Cl)c(Cl)c3)c2o1
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Compound Formula C17H8Cl2FNO5
Compound Structure
Protein Name
G-protein coupled receptor 35
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Carboxylic acid receptor
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Kynurenic acid receptor
Uniprot ID
Q9HC97
Gene Name
GPR35
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
EC50 = 106 nM
   TI
   LI
   LO
   TS
2
EC50 = 117 nM
   TI
   LI
   LO
   TS
3
Ki = 11.5 nM
   TI
   LI
   LO
   TS