Brief Information of the Compound and Protein
Compound Name
N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
    Show/Hide
PubChem ID
CID: 73294314
Canonical SMILES
Clc1cnc(Nc2cccc(NC(=O)C=C)c2)nc1-c1c[nH]c2ccccc12
    Show/Hide
Compound Formula C21H16ClN5O
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000323 LoVo Homo sapiens (Human)  1
1
IC50 = 3500 nM
   TI
   LI
   LO
   TS
CL000157 NCI-H1975 Homo sapiens (Human)  1
1
IC50 = 81 nM
   TI
   LI
   LO
   TS