Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[2H]-(1R,3S,4S,5R)-3-{4-Amino-3-fluoro-5-[2,2,2-trifluoro-1-((R)-methoxymethyl)-ethoxy]-benzyl}-5-(3-isopropyl-benzylamino)-1-oxo-tetrahydro-thiopyran-4-ol
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 PubChem ID
CID: 72191659
Canonical SMILES
[2H]C([2H])(N[C@H]1C[S@+]([O-])C[C@@H](Cc2cc(F)c(N)c(O[C@H](COC)C(F)(F)F)c2)[C@@H]1O)c1cccc(C(C)C)c1
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Compound Formula C26H34F4N2O4S
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM