Brief Information of the Compound and Protein
Compound Name |
(2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]amino]butan-1-ol
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PubChem ID | |||||
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Compound Structure |
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Protein Name |
Cyclin-dependent kinase 2
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Protein Classification |
Enzyme
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Kinase
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Protein Kinase
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CMGC protein kinase group
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CMGC protein kinase CDK family
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CMGC protein kinase CDC2 subfamily
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Uniprot ID | Gene Name | CDK2 |
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID | Cell Line Name | Cell Line Organism | |
CL000012 | Sf21 | Spodoptera frugiperda (Fall armyworm) | 1 |
1 |
IC50 = 500 nM
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TI
LI
LO
TS
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Biochemical Assays
1 | IC50 = 90 nM | ||
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2 | IC50 = 100 nM | ||
3 | IC50 = 220 nM | ||
4 | IC50 = 370 nM | ||
5 | IC50 = 400 nM | ||
6 | IC50 = 600 nM | ||
7 | IC50 = 700 nM | ||
8 | Kd = 2900 nM | ||
9 | Kd = 3400 nM |