Brief Information of the Compound and Protein
Compound Name
3-[1-[(4-fluorophenyl)methyl]pyrazol-4-yl]-5-(1-methylpyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
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PubChem ID
CID: 71818271
Canonical SMILES
Cn1cc(cn1)-c1cnc2[nH]cc(-c3cnn(Cc4ccc(F)cc4)c3)c2c1
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Compound Formula C21H17FN6
Compound Structure
Protein Name
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000300 Karpas-299 Homo sapiens (Human)  2
1
IC50 = 3011 nM
   TI
   LI
   LO
   TS
2
IC50 = 3914 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 70 nM
2 IC50 = 256.4 nM