Brief Information of the Compound and Protein
Compound Name
4-[3-cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-amine
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PubChem ID
CID: 11681588
SID: 16785736
Canonical SMILES
Nc1nccc(n1)-c1c(ncn1C1CCCCC1)-c1ccc(F)cc1
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Compound Formula C19H20FN5
Compound Structure
Protein Name
Casein kinase I isoform delta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CK1 protein kinase group
>
CK1 protein kinase CK1 family
Uniprot ID
P48730
Gene Name
CSNK1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 80.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.8 nM
2 IC50 = 13 nM
3 IC50 = 32 nM
4 IC50 = 80 nM