Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
    Show/Hide
 PubChem ID
CID: 5360515
SID: 14875729
Canonical SMILES
Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O
    Show/Hide
Compound Formula C20H23NO4
Compound Structure
Protein Name
 Protein Info 
Mu-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P42866
Gene Name
OPRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  6
1
EC50 = 0.16 nM
   TI
   LI
   LO
   TS
2
IC50 = 6.62 nM
   TI
   LI
   LO
   TS
3
Ki = 0.33 nM
   TI
   LI
   LO
   TS
4
Ki = 0.39 nM
   TI
   LI
   LO
   TS
5
Ki = 0.4 nM
   TI
   LI
   LO
   TS
6
Ki = 0.7 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.6457 nM
   TI
   LI
   LO
   TS