Brief Information of the Compound and Protein
Compound Name
N-(4-methylpyridin-2-yl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine
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PubChem ID
CID: 59186270
Canonical SMILES
CC(C)c1cccc(c1)-c1cccc2nc(Nc3cc(C)ccn3)nn12
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Compound Formula C21H21N5
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2 Homo sapiens (Human)  1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 40.6 nM