Brief Information of the Compound and Protein
Compound Name
4-[[8-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzoic acid
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PubChem ID
CID: 44555004
SID: 87238411
Canonical SMILES
COc1ccc(cc1)-c1cccn2nc(Nc3ccc(cc3)C(O)=O)nc12
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Compound Formula C20H16N4O3
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2 Homo sapiens (Human)  1
1
IC50 = 212 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.7 nM