Brief Information of the Compound and Protein
Compound Name
[4-[[5-(1-ethylpyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]pyridin-2-yl]methanol
    Show/Hide
PubChem ID
CID: 59186263
Canonical SMILES
CCn1cc(cn1)-c1cccc2nc(Nc3ccnc(CO)c3)nn12
    Show/Hide
Compound Formula C17H17N7O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2 Homo sapiens (Human)  1
1
IC50 = 115 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3 nM