Brief Information of the Compound and Protein
Compound Name
(2R)-2-[4-[[8-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]pyrazol-1-yl]propan-1-ol
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PubChem ID
CID: 59199061
Canonical SMILES
COc1ccc(cc1)-c1cccn2nc(Nc3cnn(c3)[C@H](C)CO)nc12
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Compound Formula C19H20N6O2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2 Homo sapiens (Human)  1
1
IC50 = 89 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.4 nM