Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8501936, 82
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 PubChem ID
CID: 59186482
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2nc3cccc(-c4cccc(c4)S(C)(=O)=O)n3n2)cc1
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Compound Formula C24H26N6O2S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 73.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9.2 nM
2 Ki = 2 nM