Brief Information of the Compound and Protein
Compound Name
7-methyl-2-[(4-methylcyclohexyl)amino]-7,8-dihydro-6H-quinazolin-5-one
    Show/Hide
PubChem ID
SID: 136919369
Canonical SMILES
C[C@H]1CC[C@@H](CC1)Nc1ncc2C(=O)CC(C)Cc2n1
    Show/Hide
Compound Formula C16H23N3O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1130 nM
   TI
   LI
   LO
   TS