Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(7-methyl-5-oxo-7,8-dihydro-6H-quinazolin-2-yl)amino]benzonitrile
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 PubChem ID
CID: 57388899
SID: 136919021
Canonical SMILES
CC1CC(=O)c2cnc(Nc3ccc(cc3)C#N)nc2C1
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Compound Formula C16H14N4O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 83.1 nM
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