Brief Information of the Compound and Protein
Compound Name
2-(4-chloroanilino)-7,7-dimethyl-6,8-dihydroquinazolin-5-one
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PubChem ID
CID: 57389059
SID: 136919187
Canonical SMILES
CC1(C)CC(=O)c2cnc(Nc3ccc(Cl)cc3)nc2C1
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Compound Formula C16H16ClN3O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 245 nM
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