Brief Information of the Compound and Protein
Compound Name
3-[(5-oxo-7,8-dihydro-6H-quinazolin-2-yl)amino]benzonitrile
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PubChem ID
CID: 57388819
SID: 136918935
Canonical SMILES
O=C1CCCc2nc(Nc3cccc(c3)C#N)ncc12
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Compound Formula C15H12N4O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 272 nM
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