Brief Information of the Compound and Protein
Compound Name
6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinolin-5-one
    Show/Hide
PubChem ID
CID: 16065021
SID: 24706320
Canonical SMILES
CC1(C)CCc2nc(ccc2C1=O)C#Cc1ccccc1
    Show/Hide
Compound Formula C19H17NO
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 23.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM