Brief Information of the Compound and Protein
Compound Name
 Compound Info 
SB-258585
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 PubChem ID
CID: 3248571
SID: 14835051
Canonical SMILES
COc1ccc(NS(=O)(=O)c2ccc(I)cc2)cc1N1CCN(C)CC1
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Compound Formula C18H22IN3O3S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
2
Ki = 2.512 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2.512 nM