Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R,E)-4'-(3-(hydroxyimino)-3-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1-o-tolylpropyl)biphenyl-4-carboxylic acid
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 PubChem ID
CID: 56601732
SID: 134335320
Canonical SMILES
Cc1ccccc1[C@H](C/C(=N\O)c1ccc(=O)n(C)c1)c1ccc(-c2ccc(C(=O)O)cc2)cc1
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Compound Formula C29H26N2O4
Compound Structure
Protein Name
 Protein Info 
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 60 nM
   TI
   LI
   LO
   TS
CL000126 NCI-H716
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2000 nM
   TI
   LI
   LO
   TS