Brief Information of the Compound and Protein
Compound Name
4'-(3-(hydroxyimino)-3-(2-methylpyridin-4-yl)-1-o-tolylpropyl)biphenyl-4-carboxylic acid
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PubChem ID
CID: 136167037
Canonical SMILES
Cc1cc(/C(CC(c2ccc(-c3ccc(C(=O)O)cc3)cc2)c2ccccc2C)=N/O)ccn1
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Compound Formula C29H26N2O3
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
CL000126 NCI-H716 Homo sapiens (Human)  1
1
EC50 = 580 nM
   TI
   LI
   LO
   TS