Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-(4-(dimethylamino)phenyl)-3-phenyl-1-(pyridin-4-yl)propan-1-one oxime
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 PubChem ID
CID: 136166859
Canonical SMILES
CN(C)c1ccc(C(C/C(=N\O)c2ccncc2)c2ccccc2)cc1
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Compound Formula C22H23N3O
Compound Structure
Protein Name
 Protein Info 
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 45 nM
   TI
   LI
   LO
   TS
CL000126 NCI-H716
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2900 nM
   TI
   LI
   LO
   TS