Brief Information of the Compound and Protein
Compound Name
3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
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PubChem ID
CID: 449193
SID: 14879303
Canonical SMILES
FC(F)Oc1ccc(cc1OCC1CC1)C(=O)Nc1c(Cl)cncc1Cl
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Compound Formula C17H14Cl2F2N2O3
Compound Structure
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 4
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Phosphodiesterase 4A
Uniprot ID
P27815
Gene Name
PDE4A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 0.35 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.21 nM
2 IC50 = 0.59 nM