Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[6-amino-7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-3-yl]-3,6-dihydro-2H-pyridine-1-carboxamide
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 PubChem ID
CID: 44181654
SID: 85170822
Canonical SMILES
C[C@@H](Oc1c(N)ncc2c(coc12)C1=CCN(CC1)C(N)=O)c1c(Cl)ccc(F)c1Cl
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Compound Formula C21H19Cl2FN4O3
Compound Structure
Protein Name
 Protein Info 
ALK tyrosine kinase receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
Q9UM73
Gene Name
ALK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000300 Karpas-299
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM