Brief Information of the Compound and Protein
Compound Name
7-[1-(2,6-dichloro-3-fluorophenyl)but-3-enoxy]-3-(1-piperidin-4-ylpyrazol-4-yl)furo[3,2-c]pyridin-6-amine
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PubChem ID
CID: 57812481
Canonical SMILES
Nc1ncc2c(coc2c1OC(CC=C)c1c(Cl)ccc(F)c1Cl)-c1cnn(c1)C1CCNCC1
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Compound Formula C25H24Cl2FN5O2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000413 MKN45 Homo sapiens (Human)  1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM