Brief Information of the Compound and Protein
Compound Name
4-[6-amino-7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-3-yl]-3,6-dihydro-2H-pyridine-1-sulfonamide
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PubChem ID
CID: 57812551
Canonical SMILES
C[C@@H](Oc1c(N)ncc2c(coc12)C1=CCN(CC1)S(N)(=O)=O)c1c(Cl)ccc(F)c1Cl
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Compound Formula C20H19Cl2FN4O4S
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000413 MKN45 Homo sapiens (Human)  1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1000 nM