Brief Information of the Compound and Protein
Compound Name
(R/S)-2-(3-(5-bromo-2-(4-(3,4-dimethylpiperazin-1-yl)-3-methoxyphenylamino)pyrimidin-4-yl)phenyl)acetonitrile
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PubChem ID
CID: 71713618
Canonical SMILES
COc1cc(Nc2ncc(Br)c(-c3cccc(CC#N)c3)n2)ccc1N1CCN(C)C(C)C1
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Compound Formula C25H27BrN6O
Compound Structure
Protein Name
Serine/threonine-protein kinase PAK 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase PAKA subfamily
Uniprot ID
Q13153
Gene Name
PAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000249 OVCAR-3 Homo sapiens (Human)  1
1
EC50 = 1060 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 61 nM