Brief Information of the Compound and Protein
Compound Name
5-[[5-chloro-4-[3-(cyanomethyl)phenyl]pyrimidin-2-yl]amino]-2-(4-methylpiperazin-1-yl)benzoic acid
    Show/Hide
PubChem ID
CID: 71713472
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(n2)-c2cccc(CC#N)c2)cc1C(O)=O
    Show/Hide
Compound Formula C24H23ClN6O2
Compound Structure
Protein Name
Serine/threonine-protein kinase PAK 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase PAKA subfamily
Uniprot ID
Q13153
Gene Name
PAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000249 OVCAR-3 Homo sapiens (Human)  1
1
EC50 = 16800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11300 nM