Brief Information of the Compound and Protein
Compound Name
(2S)-1-N-[5-(2-tert-butylpyrimidin-4-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
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PubChem ID
CID: 71682651
Canonical SMILES
Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1ccnc(n1)C(C)(C)C
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Compound Formula C18H24N6O2S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000019 Rat1 Rattus norvegicus (Rat)  1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1800 nM
2 IC50 = 1900 nM
3 IC50 = 2010 nM