Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-4-phenylbenzamide
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 PubChem ID
CID: 71733935
Canonical SMILES
CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C
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Compound Formula C28H34N2O
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  5
1
Ki = 1.2 nM
   TI
   LI
   LO
   TS
2
Ki = 3.9 nM
   TI
   LI
   LO
   TS
3
Ki = 9.4 nM
   TI
   LI
   LO
   TS
4
Ki = 14 nM
   TI
   LI
   LO
   TS
5
Ki = 21 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 16 nM
   TI
   LI
   LO
   TS
2
EC50 = 92 nM
   TI
   LI
   LO
   TS
3
EC50 = 130 nM
   TI
   LI
   LO
   TS
4
EC50 = 1300 nM
   TI
   LI
   LO
   TS
5
EC50 = 1500 nM
   TI
   LI
   LO
   TS