Brief Information of the Compound and Protein
Compound Name
cyclohexylmethyl((S)-3-((S)-1-(3,4-dichlorophenyl)ethylamino)-2-hydroxypropyl)phosphinic acid hydrochloride
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PubChem ID
CID: 197583
SID: 14906174
Canonical SMILES
C[C@H](NC[C@H](O)CP(=O)(O)CC1CCCCC1)c1ccc(Cl)c(Cl)c1.Cl
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Compound Formula C18H29Cl3NO3P
Compound Structure
Protein Name
Gamma-aminobutyric acid type B receptor subunit 1
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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GABA-B receptor
Uniprot ID
Q9UBS5
Gene Name
GABBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 6.4 nM
   TI
   LI
   LO
   TS
2
Ki = 2.9 nM
   TI
   LI
   LO
   TS