Brief Information of the Compound and Protein
Compound Name
[4-fluoro-2-[(2S)-3-(5-fluorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]phenyl]-[(3S)-3-hydroxypyrrolidin-1-yl]methanone
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PubChem ID
CID: 68963562
Canonical SMILES
O[C@H](COc1cc(F)ccc1C(=O)N1CC[C@H](O)C1)CN1CCC2(Cc3cc(F)ccc3O2)CC1
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Compound Formula C26H30F2N2O5
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 12 nM
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