Brief Information of the Compound and Protein
Compound Name
N-[2-[(2S)-3-(5-fluorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]acetamide
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PubChem ID
CID: 10094212
SID: 15081543
Canonical SMILES
CC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(Cc3cc(F)ccc3O2)CC1
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Compound Formula C23H27FN2O5
Compound Structure
Protein Name
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 0.52 nM
   TI
   LI
   LO
   TS
CL000040 THP-1 Homo sapiens (Human)  2
1
IC50 = 0.52 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.6 nM
   TI
   LI
   LO
   TS