Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ACT-129968
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 PubChem ID
CID: 49843471
SID: 104171432
Canonical SMILES
OC(=O)Cn1c2CCN(Cc2c2cc(F)ccc12)C(=O)c1cccc2ccccc12
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Compound Formula C24H19FN2O3
Compound Structure
Protein Name
 Protein Info 
Prostaglandin D2 receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
Q9Y5Y4
Gene Name
PTGDR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
2
IC50 = 30 nM
   TI
   LI
   LO
   TS
3
IC50 = 80 nM
   TI
   LI
   LO
   TS
4
IC50 = 340 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 235 nM