Brief Information of the Compound and Protein
Compound Name
2-[2-[4-(4-ethylphenyl)benzoyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid
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PubChem ID
CID: 11539410
SID: 16641521
Canonical SMILES
CCc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCc2c(C1)c1ccccc1n2CC(O)=O
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Compound Formula C28H26N2O3
Compound Structure
Protein Name
Prostaglandin D2 receptor 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
Q9Y5Y4
Gene Name
PTGDR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  4
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 7 nM
   TI
   LI
   LO
   TS
3
IC50 = 190 nM
   TI
   LI
   LO
   TS
4
IC50 = 320 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 240 nM