Brief Information of the Compound and Protein
Compound Name
2-[4-[2-(5-methyl-2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]pyrazol-1-yl]ethanol
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PubChem ID
CID: 58204711
Canonical SMILES
CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)-c1cnn(CCO)c1
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Compound Formula C22H25N7O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000918 MCF7-neo/Her2 Homo sapiens (Human)  1
1
IC50 = 4.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.4 nM