Brief Information of the Compound and Protein
Compound Name
2-[4-[2-[2-(2,2,2-trifluoroethyl)-1,2,4-triazol-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]pyrazol-1-yl]ethanol
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PubChem ID
CID: 58204974
Canonical SMILES
OCCn1cc(cn1)-c1ccc2-c3nc(cn3CCOc2c1)-c1ncnn1CC(F)(F)F
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Compound Formula C20H18F3N7O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000918 MCF7-neo/Her2 Homo sapiens (Human)  1
1
IC50 = 2.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki < 1 nM